It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling

Carvalho, Ana Luisa and Fernandes, Dominique (2021) It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling. PLOS Biology, 19 (11). e3001448. ISSN 1545-7885

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Abstract

Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediate synaptic scaling.

Item Type: Article
Subjects: Journal Eprints > Biological Science
Depositing User: Managing Editor
Date Deposited: 02 Mar 2023 06:29
Last Modified: 05 Mar 2024 03:58
URI: http://repository.journal4submission.com/id/eprint/1086

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