Rare Polypoid Disease of the Gastro Intestinal Tract– Cronkhite–Canada Syndrome

Cronkhite–Canada syndrome is a rare condition with multiple hamartomatous polyps in the gastrointestinal tract; need to be differentiated, from other conditions with similar symptoms and polypoid lesions. 52 year old male patient presented with anorexia and weight loss, discovered to be having multiple polypoid lesions in the stomach, duodenum, colon and terminal ileum with histological features of Cronkhite–Canada syndrome. He later developed diarrhoea and characteristic ectodermal signs of CCS. He was treated with prednisolone, sulfasalazine. Nevertheless, the disease was steroid resistant and developed recurrent pneumonia and Candidemia and finally succumbed due to the malnutrition and the infections.