Carotid artery intima media thickness and HsCRP: Predictors for atherosclerosis in prediabetic patients

Parildar, Hulya and Gulmez, Oyku and Cigerli, Ozlem and Unal, Aslı Dogruk and Erdal, Rengin and Demirag, Nılgun Guvener (2013) Carotid artery intima media thickness and HsCRP: Predictors for atherosclerosis in prediabetic patients. Pakistan Journal of Medical Sciences, 29 (2). ISSN 1681-715X

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Abstract

Objective: We aimed to assess carotid intima media thickness (CIMT) and serum high-sensitivity C-reactive protein (hs-CRP) levels as estimated markers of subclinical atherosclerosis and inflammation in prediabetic patients.

Methodology: One hundred and ten patients were defined as prediabetic and seventy-six subjects (age and sex matched) were assigned as control group in our cross sectional study. Bilateral CIMT measurements and hs-CRP levels were evaluated.

Results: The prevalance of hypertension, hyperlipidemia, angiotensin receptor blockers and antihyperlipidemic medication use were statistically higher in the prediabetic group. Serum hs-CRP levels, left, right and maximum CIMT were statistically higher among prediabetics compared to control group. There was a positive, significant correlation between left, right, maximum CIMT and fasting blood glucose, HbA1c, hs-CRP levels and BMI.

Conclusion: Recognising and focusing on the intervention of prediabetic state as early as possible and identifying the susceptible patients who may benefit from more aggressive preventive therapy is an important issue of primary prevention of diabetes and cardiovascular diseases.

Item Type: Article
Subjects: Journal Eprints > Medical Science
Depositing User: Managing Editor
Date Deposited: 16 May 2023 05:24
Last Modified: 25 Jan 2024 04:04
URI: http://repository.journal4submission.com/id/eprint/2024

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