Biomaterials and biotechnology for periodontal tissue regeneration: Recent advances and perspectives

Deng, Rong and Xie, Yuzheng and Chan, Unman and Xu, Tao and Huang, Yue (2022) Biomaterials and biotechnology for periodontal tissue regeneration: Recent advances and perspectives. Journal of Dental Research, Dental Clinics, Dental Prospects, 16 (1). pp. 1-10. ISSN 2008-210X

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Abstract

Periodontal tissues are organized in a complex three-dimensional (3D) architecture, including the alveolar bone, cementum, and a highly aligned periodontal ligament (PDL). Regeneration is difficult due to the complex structure of these tissues. Currently, materials are developing rapidly, among which synthetic polymers and hydrogels have extensive applications. Moreover, techniques have made a spurt of progress. By applying guided tissue regeneration (GTR) to hydrogels and cell sheets and using 3D printing, a scaffold with an elaborate biomimetic structure can be constructed to guide the orientation of fibers. The incorporation of cells and biotic factors improves regeneration. Nevertheless, the current studies lack long-term effect tracking, clinical research, and in-depth mechanistic research. In summary, periodontal tissue engineering still has considerable room for development. The development of materials and techniques and an in-depth study of the mechanism will provide an impetus for periodontal regeneration.

Item Type: Article
Subjects: Journal Eprints > Medical Science
Depositing User: Managing Editor
Date Deposited: 25 May 2023 09:15
Last Modified: 11 Jan 2024 04:23
URI: http://repository.journal4submission.com/id/eprint/2106

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