Spectrum of Hypertriglyceridemia at the Onset of Type 2 Diabetes in Ouagadougou

Guira, Oumar and Bognounou, Réné and Zoungrana, Lassané and Tonde, Aline and Nagalo, André and Traore, Réné and Drabo, Joseph Youssouf (2020) Spectrum of Hypertriglyceridemia at the Onset of Type 2 Diabetes in Ouagadougou. Open Journal of Internal Medicine, 10 (01). pp. 83-89. ISSN 2162-5972

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Abstract

Introduction: Hypertriglyceridemia is a frequent dyslipidemia in type 2 diabetes. We aimed to determine its prevalence, its typology, and its associated factors in newly type 2 diabetes patients in Ouagadougou. Material and Method: This cross-sectional, descriptive and analytic study has been performed from May 2015 to June 2016 in the Internal medicine department in Yalgado Ouédraogo teaching hospital, Ouagadougou. An accidental sample of newly type 2 diabetes outpatients, na?ve of antidiabetics therapy was studied. A 12-hour fasting triglyceridemia was performed; hypertriglyceridemia was defined for triglyceridemia > 1.5 g/L (1.7 mmol/L). Data were analyzed with Epi info 7.1.5.0. Proportions and means were compared respectively with Khi2 or Fisher’s test and Student’s test with a significance of p < 5%. Results: One hundred and three patients, i.e. 35 (34%) men and 68 (66%) women were included. The sex ratio was 0.51 and the mean age 49.3 ± 10.1 years [limits: 24 and 70]. The mean value of triglyceridemia was 1.8 ± 1.7 mmol/L [limits: 0.5 and 14.9]. Hypertriglyceridemia was reported in 32 patients (31.1%): minor (<4.52 mmol/L) in 26 (81.3%), moderate (between 4.52 and 11.30 mmol/L) in five (15.6%) and severe (>11.30 mmol/L) in one (3.1%) patients. Hypertriglyceridemia’s phenotype was commonly integrated into a mixed dyslipidemia; it was often combined with a total cholesterolemia increase and a HDL cholesterolemia decrease. In bivariate analysis, hyperglycemia was associated with severe hyperglycemia (p = 0.006) and renal failure (p = 0.03). Conclusion: Hypertriglyceridemia in type 2 diabetes is frequent and often combined with other lipids disorders. It may need an optimal care.

Item Type: Article
Subjects: Journal Eprints > Medical Science
Depositing User: Managing Editor
Date Deposited: 07 Jun 2023 04:57
Last Modified: 10 Jan 2024 04:02
URI: http://repository.journal4submission.com/id/eprint/2195

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