Physiological Features of Hemostasis in Newborn Calves Receiving Ferroglukin, Fosprenil and Hamavit, for Iron Deficiency

Newborn calves still often suffer from iron deficiency. This state damages their growth and development - to some extent, due to the development of pathological changes in hemostasis. Thereby, both veterinary science and cattle physiology give great scientific and practical significance to the search of approaches to effective correction of new-born calves’ hemostasis pathology connected with iron deficiency. It seemed to be perspective to evaluate the influence degree of ferroglukin, traditionally applied at iron deficiency, in combination with metabolism stimulators (fosprenil and hamavit) on new-born calves’ indices of hemostasis system. During our study it was established that new-born calves with iron deficiency were also characterized by decreased plasma antioxidant protect-ability, intensity of lipids’ peroxidation processes, increase of platelets’ hemostatic activity and blood coagulation system along with the decrease of vascular wall’s ability to bind it. In our study we found that combination of ferroglukin, fosprenil and hamavit given to new-born calves with iron deficiency showed improved plasma antioxidant and lipid peroxidation activity. Normalization of platelet activity, positive dynamics of hemostasis vascular and plasma components were also observed. Iron deficiency of new-born calves can be considered as the model of hemostasis abnormality. With its help we could try different means and their combinations to cure the pathology of hemostasis. The obtained results allowed us to consider the usage of fosprenil and hamavit combination on the background of ferroglukin to be sufficient for reducing the pathology of hemostasis in newborn calves with iron deficiency.