EVALUATING THE ANTIBACTERIAL ACTIVITY OF MORINDA MORINDOIDES EXTRACTS ON THE IN VITRO GROWTH OF THE CLINICAL STRAINS OF Shigella sp.

For a couple of years, strains of Shigella resistant to aminopenicillins and cotrimoxazole have developed and have become predominant.

The purpose of paper is to show the social contribution in the care of gastroenteritis. As such, the antibacterial activity of the total aqueous and 70% ethanolic extracts of the leaves of Morinda morindoides, a plant from the Ivorian pharmacopoeia was evaluated.

In this paper, bacteriological tests were carried out on two pathogenic strains of Shigella sp. (EEQ and 1055).

The methods of diffusion, either in agar medium or in liquid, were used for the search for Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC).

The results show that both extracts tested have in vitro antibacterial bactericidal efficiency on both Shigella sp. strains. However, the 70% ethanolic extract which is twice as effective as the total aqueous extract is more active against strains of Shigella Sp tested, with a MBC of 25 mg/mL.

The finding suggest that antibacterial properties of this plant could also useful for caring shigellosis.