Recent Advances on Topical Application of Ceramides to Restore Barrier Function of Skin

Kahraman, Emine and Kaykın, Melis and Şahin Bektay, Hümeyra and Güngör, Sevgi (2019) Recent Advances on Topical Application of Ceramides to Restore Barrier Function of Skin. Cosmetics, 6 (3). p. 52. ISSN 2079-9284

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Abstract

Human skin is the largest organ of the body and is an effective physical barrier keeping it from environmental conditions. This barrier function of the skin is based on stratum corneum, located in the uppermost skin. Stratum corneum has corneocytes surrounded by multilamellar lipid membranes which are composed of cholesterol, free fatty acids and ceramides (CERs). Alterations in ceramide content of the stratum corneum are associated with numerous skin disorders. In recent years, CERs have been incorporated into conventional and novel carrier systems with the purpose of exogenously applying CERs to help the barrier function of the skin. This review provides an overview of the structure, function and importance of CERs to restore the barrier function of the skin following their topical application.

Item Type: Article
Subjects: Journal Eprints > Medical Science
Depositing User: Managing Editor
Date Deposited: 22 Mar 2023 05:45
Last Modified: 02 May 2024 09:12
URI: http://repository.journal4submission.com/id/eprint/914

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